Not in dependent status. TD dependants may accompany the principal and may study, but they are not authorized to work, whatever their qualifications or the employer's willingness.
Her route has to be built separately
A household where both adults work in the same field often assumes that one application covers the family, and that assumption is wrong in this classification. She would need her own basis, which means either a classification she qualifies for in her own right, or accepting that she will not be employed for the period of the assignment. Whether her own occupation appears in the profession list is the first question, and if it does not, the list cannot be extended by argument. Children in dependent status may attend school. Because this consequence follows from the principal's route rather than from anything about her, it is worth weighing before the route is chosen if alternatives exist.
Hypothetical example: A Canadian statistician accepts a temporary research role while her spouse intends to continue paid online translation work from their United States home. The household must decide before moving whether the spouse has an independent work-authorized status; dependent status does not make remote paid work permissible merely because clients are elsewhere. The relevant records are the spouse’s actual contracts, work location, and proposed status. Waiting until invoices are due turns a planning question into a compliance problem that the principal’s admission cannot solve.